Establish a European platform for training scientists and students in Bioluminiscence Imaging.

LUMC has two bioluminiscent imaging systems available that use different principals and is one few places in Europe who have a high field magnetic resonance microscope (MRM). The magnification is given by ultra-field magnets that are available, the largest reaching 17.6 Tesla(Bruker). This specific machine results from an earlier European-funded project (Prof. Dr. H. de Groot, Leiden).

Over the first 18 months period, the Leiden Technological Platform will act as a test and demonstrations centre and will validate the following equipements:

• Cell-viZio prototype, which will be marketed in the next couple of months by Mauna Kea technology ( partner 38, MKT, France), to test its use in tracking GFP-expressing tumor cells.
• PhotoImaging system from BIOSPACE (Partner 6, BIOSP, France), to test the new luciferase expressing tumor cell clones and to make a comparison with other BLI systems already available in Leiden.

The training will be given to groups of max 5 trainees. The entire training activities might take from 2 full man.months and 1 month of laboratory time for the first year, involving both postdoc and engineer staff time, to 4 full man.months and 2 months of laboratory time for the following years as trainings sessions will be progressively added over the duration of the project.